TARGET SPECIES: Hens.
INDICATIONS: For active immunization against the Newcastle disease in hens in order to reduce the mortality and clinical signs caused by the Newcastle disease virus.
Immunity develops as of 7 days after vaccination and lasts for 49 days.
1 dose contains:
The Newcastle disease virus, the clone lentogenic strain LS79: min. 106.5 – max. 107 EID50
EID50 = 50% egg infective dose.
Chickens vaccinated by aerosols exhibit slight respiratory symptoms (20-25%) which go away after 2-3 days, and chickens vaccinated by ocular instillation exhibit slight conjunctivitis to a low degree (10-15%).
The frequency of adverse reactions is defined using the following convention:
- Very frequent (more than 1 in 10 animals experiencing adverse reactions during treatment);
- Frequent (more than 1, but less than 10 in 100 animals);
- Less frequent (more than 1, but less than 10 in 1,000 animals);
- Rare (more than 1, but less than 10 in 10,000 animals);
- Very rare (less than 1 in 10,000 animals, including isolated reports).
Individual ocular/intranasal administration:
For day old chickens.
Reconstitute the vaccine in 30 ml for 1000 doses.
In order to prepare the vaccine suspension for administration purposes, remove the aluminum cap and the rubber stopper from the lyophilized product bottle; then, add an amount of the diluent, and, then, reapply the rubber stopper and stir vigorously. Transfer the resulting suspension to the diluent bottle and immediately start administering the vaccine to the birds.
Administer by dropper at a rate of one drop per chicken in one eye. Hold the chicken so that one eye should be facing upwards and allow a drop of the vaccine to fall into the eye. Chickens should swallow during vaccination. Administration in the drinking water (10 or 11-day-old chickens):
- 48 hours before vaccination and 24 hours after vaccination, stop any other administration of veterinary medicinal products or disinfectants in the drinking water;
- Rinse the drinking troughs with clean fresh water, without the addition of veterinary medicinal products or disinfectants;
- 2 hours before vaccination, deprive the birds of water;
- Add the vaccine reconstituted with diluent to the clean fresh drinking water, without the addition of veterinary medicinal products or disinfectants, assessing the amount of water that a bird drinks: 10 ml/chicken up to 30 days of age; 20 ml/chicken after 30 days of age (e.g. 250 doses/5 l of water, 500 doses/10 l of water);
- Do not re-administer water until all the water containing the vaccine has been consumed; afterwards, proceed with the usual watering practice;
Aerosol (spraying) administration:
Dissolve the vaccine in clean cold water, free from any traces of chlorine or iron. Open the bottles and dilute the vaccine as follows: for chickens older than one day: 1000 doses in 1000 ml of water; adjust the nozzle to release drops that produce fine mist. The aerosol dispenser should not exhibit any sediments or traces of corrosion or disinfectants. The vaccine solution should be sprayed evenly over the birds from a distance of 30 to 40 cm, preferably when they are grouped together.
Administer a dose of vaccine/chicken via the ocular/intranasal route, in the drinking water or by way of aerosols (spraying). Never use less than one dose of vaccine/chicken. The volume of vaccine used for administration depends on the equipment used and the age of the birds to be vaccinated.
Meat and offal: zero days.
Keep out of the reach and sight of children. Store and transport refrigerated (2-8°C). Keep the product away from direct sunlight and in a dry place. The shelf life after dilution or reconstitution as instructed: to be administered immediately.
Boxes x 10 bottles x3 ml, x6 ml.
Not all pack sizes may be marketed.